Mad as a Hatter
The term "mad as a hatter" will forever be linked to the madcap milliner
in Lewis Carroll's classic children's book, Alice in Wonderland. But
few actually know that the true origin of the saying relates to a
disease peculiar to the hat making industry in the 1800s. A mercury
solution was commonly used during the process of turning fur into felt,
which caused the hatters to breathe in the fumes of this highly toxic
metal, a situation exacerbated by the poor ventilation in most of the
workshops. This led in turn to an accumulation of mercury in the
workers' bodies, resulting in symptoms such as trembling (known as
"hatters' shakes"), loss of coordination, slurred speech, loosening of
teeth, memory loss, depression, irritability and anxiety -- "The Mad
Hatter Syndrome." The phrase is still used today to describe the effects
of mercury poisoning, albeit from other sources
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